Summary Role of natural herbs in the treatment of hypertension - PMC www.ncbi.nlm.nih.gov
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Natural herbs and dietary changes can be used as an alternative or complementary treatment for hypertension, but more scientific research is needed to verify their effectiveness and safety profile, and it's important to consult with a healthcare professional before using them.
Key Points
- Natural herbs, such as garlic, hawthorn, and ginger, have been found to lower blood pressure and may be used as a complementary treatment for hypertension.
- Further research is needed to verify the safety and efficacy of herbal remedies for hypertension.
- Lifestyle changes, medications, and natural herbs with hypotensive properties are treatment options for essential hypertension.
- Secondary hypertension is caused by identifiable conditions and is treated differently than essential hypertension.
- Various natural herbs, including Lavandula stoechas and Hibiscus sabdariffa, have reliable evidence of antihypertensive effects.
Summaries
307 word summary
This article discusses the potential benefits of natural herbs in treating hypertension. Various herbs, such as Hibiscus sabdariffa, Lepidium latifolium, Lavandula stoechas, and Corilagin, have been found to reduce blood pressure and improve cardiovascular function in humans and rats. Soy protein, isoflavones, and dietary changes such as increased protein and soluble fiber intake can also benefit cardiovascular health. Additionally, various plants such as pomegranate, radish seed, French maritime pine bark, and tomato have been studied for their effects on hypertension. Several other herbs, including ginger, Vitex doniana bark, Viscum album leaves, whole-grain diets, chocolate, Solanum sisymbriifolium, Rhaptopetalum coriaceum Oliv, and sesame seeds, have also shown antihypertensive effects in various studies. The article concludes that natural herbs and dietary changes can be used as an alternative or complementary treatment for hypertension. The use of natural herbs, including celery, garlic, buchu, and hawthorn, has been found to lower blood pressure. Some extracts produce a hypotensive activity through vasorelaxation resulting from nitrous oxide stimulation or blockade of calcium channels, while others show antioxidant activity and a tonic action on cardiac myocytes. Grataegic acid was identified as the hypotensive principle in Crataegus. However, more scientific research needs to be done to verify the effectiveness and safety profile of such herbal remedies. It is important to consult with a healthcare professional before using these herbs as they may interact with other medications. Hypertension can lead to serious health conditions such as heart disease, stroke, kidney disease, and blindness. Essential hypertension is the most common type and can be caused by factors such as obesity, sedentary lifestyle, stress, and potassium deficiency. Treatment options include lifestyle changes, medications, and natural herbs with hypotensive properties. Secondary hypertension is caused by identifiable conditions such as Cushing's syndrome or insulin resistance and is treated differently than essential hypertension by treating the underlying cause of elevated blood pressure.
665 word summary
The use of natural herbs such as garlic, hawthorn, and ginger in the treatment of hypertension is discussed. However, it is important to consult with a healthcare professional before using these herbs as they may interact with other medications. Further research is needed to verify their safety profile and efficacy as a treatment option. Hypertension can lead to serious health conditions such as heart disease, stroke, kidney disease, and blindness. Essential hypertension is the most common type and can be caused by factors such as obesity, sedentary lifestyle, stress, and potassium deficiency. Treatment options include lifestyle changes, medications, and natural herbs with hypotensive properties. Secondary hypertension is caused by identifiable conditions such as Cushing's syndrome or insulin resistance and is treated differently than essential hypertension by treating the underlying cause of elevated blood pressure. This article discusses the use of natural herbs in treating hypertension. Various herbs, including celery, garlic, buchu, and hawthorn, have been found to lower blood pressure. Studies have been conducted on local plants with hypotensive and antihypertensive therapeutic values. Some extracts produce a hypotensive activity through vasorelaxation resulting from nitrous oxide stimulation or blockade of calcium channels. Other extracts also show antioxidant activity and a tonic action on cardiac myocytes. Grataegic acid was identified as the hypotensive principle in Crataegus. In experiments with anesthetized rabbits, intravenous administration of the extract preparation lowered the BP for up to 3 hours. However, more scientific research needs to be done to verify the effectiveness and safety profile of such herbal remedies. Natural herbs have been extensively studied for their antihypertensive effects. Lavandula stoechas and Hibiscus sabdariffa have reliable evidence of antihypertensive effects. Roselle, Gossypium barbadense, Glycine max, and Fuchsia magellanica have also been found to reduce blood pressure. Tomato extract, Lumnitzera racemosa, Linum usitatissimum, and Lepidium latifolium have modest antihypertensive effects. Pycnogenol, Nela nelli, Phyllanthus amarus, Peganum harmala, Ocimum basilicum, Musanga cecropiodes, and Moringa oleifera have been shown to have hypotensive effects. Rhaptopetalum coriaceum oliver, Rauwolfia serpentina, radish extract, and pomegranate juice have also been found to have antihypertensive activity. Kudzu root is officially listed and used in China for the treatment of hypertension. Natural herbs have been found to have hypotensive effects and are being studied for their potential in the treatment of hypertension. Cocoa powder enriched with flavonoids, extract of Uncaria guianensis, root of Sesbania sesban, seeds from Sesamum indicum, and Rhododendron coriaceum have all been found to lower blood pressure. Mistletoe leaves, Viscum album leaves, and U. rhynchophylla species also contain biologically active principles that induce hypotensive effects. Ginger and Vitex doniana extracts have also been found to reduce blood pressure in rats. Additionally, dietary changes such as increased protein and soluble fiber intake have been found to reduce blood pressure. Studies have been conducted to identify potential angiotensin converting enzyme inhibitors from Indian medicinal plants. This article provides a list of natural herbs and their potential benefits in treating hypertension. Studies have shown that certain herbs, such as tomato extract, Corilagin, flaxseed, Lepidium latifolium, Lavandula stoechas, Hibiscus sabdariffa, soy protein, isoflavones, Mapuche, Clematis chinensis, Desmodium styracifolium, Daucus carota, and Cuscuta reflexa, have been effective in reducing blood pressure and improving cardiovascular function in rats and humans. The article also includes references related to the role of natural herbs in the treatment of hypertension, as well as the treatment and causes of hypertension. Overall, natural herbs and dietary changes can be used as an alternative or complementary treatment for hypertension. This article reviews natural herbs that have potential for reducing blood pressure, including Hibiscus sabdariffa, Lepidium latifolium, Lavandula stoechas, and Corilagin. Other herbs with hypotensive effects include Daucus carota and Cuscuta reflexa. Soy protein and isoflavones may also benefit cardiovascular health. The document contains references to studies on the effects of various plants on hypertension, including pomegranate, radish seed, French maritime pine bark, and tomato. Ginger, Vitex doniana bark, Viscum album leaves, whole-grain diets, chocolate, Solanum sisymbriifolium, Rhaptopetalum coriaceum Oliv, and sesame seeds have also shown antihypertensive effects in various studies.
2590 word summary
The article discusses the use of natural herbs in the treatment of hypertension. Ginger has been found to lower blood pressure through the blockade of voltage-dependent calcium channels. Extracts from the bark of Vitex doniana and leaves of Viscum album have also shown activity in reducing blood pressure. Whole-grain diets have been found to reduce blood pressure in mildly hypercholesterolemic men and women. Chocolate has also been found to reduce blood pressure in elderly individuals with isolated systolic hypertension. Extracts from Solanum sisymbriifolium and Rhaptopetalum coriaceum Oliv have shown hypotensive effects in rats. Sesamin IV, found in sesame seeds, has also shown antihypertensive effects by inhibiting vascular superoxide production. This document is a list of references to studies on the effects of natural herbs on hypertension. The studies include extracts from various plants such as pomegranate, radish seed, French maritime pine bark, and tomato, among others. The studies found that these herbs have hypotensive effects and can reduce blood pressure in patients with hypertension. Some of the herbs were found to improve endothelial function, while others had a relaxing effect on arterial pressure and peripheral circulation. This article reviews various natural herbs that have been studied for their antihypertensive effects. Studies have found that extracts from plants such as Hibiscus sabdariffa, Lepidium latifolium, Lavandula stoechas, and Corilagin have shown potential in reducing blood pressure. Additionally, compounds extracted from Daucus carota and Cuscuta reflexa have demonstrated hypotensive effects. The article also mentions the potential benefits of soy protein and isoflavones on cardiovascular health. Overall, the use of natural herbs in the treatment of hypertension is a promising area of research. This article discusses the use of natural herbs in the treatment of hypertension. Studies have shown that certain herbs, such as Crataegus, Coleus forskohlii, Castanospermum australe, Cassia occidentalis, Carum copticum, Capparis cartilaginea, and Hibiscus sabdariffa, have been effective in reducing blood pressure. In addition, dietary changes such as increasing oat and soluble fiber intake as well as consuming teas like hibiscus and garlic supplementation have also shown to have a positive impact on hypertension. Overall, natural herbs and dietary changes can be used as an alternative or complementary treatment for hypertension. This is a list of academic references related to the treatment and causes of hypertension. The references cover a range of topics including the effects of garlic on blood pressure, the role of medicinal plants in therapy, genetic basis of hypertension, obesity hypertension, and the impact of stress and exercise on blood pressure. The list includes meta-analyses, systematic reviews, and studies from various medical journals. This is a list of references related to the role of natural herbs in the treatment of hypertension, including studies on ginger, Vitex doniana, Viscum album, Uncaria rhynchophylla, Solanum sisymbriifolium, and whole-grain diets. The studies suggest that some herbs may have a hypotensive effect and could be used as a complementary treatment for hypertension. This article discusses various studies on the use of natural herbs for the treatment of hypertension. The studies mentioned include the effects of sesamin IV, Rhaptopetalum coriaceum Oliv stem bark, radish seed extract, pomegranate juice, Radix puerariae, Pueraria lobata, French maritime pine bark extract, Phyllanthus amarus, harmalol, calcium channel blockers, Musanga cecropioides stem bark, and Moringa oleifera. Some of these herbs were found to have hypotensive effects and improve cardiovascular function in rats and humans. Additionally, tomato extract was found to have antioxidant effects in hypertension patients. This article provides a list of natural herbs and their potential benefits in treating hypertension. One study found that tomato extract reduced blood pressure in patients with grade-1 hypertension. Corilagin, found in plants, was also found to have an antihypertensive effect in rats. Flaxseed was shown to reduce cardiovascular risk. Aqueous extracts of Lepidium latifolium and Lavandula stoechas were found to have diuretic and sedative effects, respectively. Hibiscus sabdariffa was found to have a blood pressure-lowering effect and to reverse cardiac hypertrophy in rats. Soy protein and isoflavones were also found to have potential benefits for cardiovascular health. Mapuche, a medicinal plant, was found to have hypotensive effects and enzyme inhibition activity. Clematis chinensis and Desmodium styracifolium were found to have hypotensive actions, while Daucus carota and Cuscuta reflexa were shown to have hypotensive effects in animal studies. This article explores the use of natural herbs in the treatment of hypertension. Studies have shown that plants such as Crataegus species, Castanospermum australe, and Carum copticum have antihypertensive effects. Additionally, dietary changes such as oat ingestion and increased protein and soluble fiber intake have been found to reduce blood pressure. Other potential treatments include alpha-amylase inhibitors from Hibiscus sabdariffa and garlic supplementation to prevent oxidative DNA damage in essential hypertension. Ethnopharmacological surveys have also been conducted to identify potential angiotensin converting enzyme inhibitors from Indian medicinal plants. This excerpt contains a list of references to studies and articles related to hypertension and natural herbs. The studies cover a variety of topics, including the effects of garlic on blood pressure, the use of medicinal plants in therapy, and the genetic basis of hypertension. Other topics covered include obesity, exercise hypertension, and the role of vitamin D in cardiovascular health. The studies come from a variety of sources, including medical journals and academic publications. The use of natural herbs in the treatment of hypertension has gained attention in recent years due to the potential for novel structures found in the biodiversity of tropical rain forests. However, only a small portion of this biodiversity has been studied for its medicinal potential. Ginger has been studied for its hypotensive effect, with chronic administration significantly reducing blood pressure in hypertensive rats. The mechanism of action involves serotonergic antagonistic properties and blockade of voltage-dependent calcium channels. Ginger also improves blood circulation and relaxes muscles surrounding blood vessels. The extract of Vitex doniana has also been found to exert a hypotensive effect in rats. The aqueous extract of mistletoe leaves was found to significantly decrease blood pressure in albino Wistar rats without altering heart rate, possibly involving sympathetic mechanisms. Viscum album leaves contain biologically active principles that induce the nitric oxide/soluble guanylate cyclase pathway and have significant coronary vasodilator activity. The hypotensive principles of V. album were found to be dihydrocadambine and isodihydrocadambine, while cadambine was inactive. The U. rhynchophylla species has a potent and long-lasting hypotensive effect in rats, attributed to an indole alkaloid called hirsutine. Hirsutine inhibits Ca2+ influx mainly through a voltage-dependent Ca2+ channel and has been found to act at the Ca2+ channels. Increasing dietary wheat bran intake by 3 to 6 g/day modestly reduces systolic and diastolic blood pressure. Cocoa powder enriched with flavonoids can lower systolic and diastolic blood pressure. Theobroma cacao can increase vasodilation and reduce endothelial dysfunction. Nuatigenosido, isolated from the extract of Uncaria guianensis, can lower blood pressure in rats. Hydroalcoholic extract from the root of Sesbania sesban can produce a significant decrease in blood pressure. Alcoholic extract of seeds from Sesamum indicum can cause hypotension in rats and may be more potent than nifedipine as a calcium channel blocker. Ethanol extract of Rhododendron coriaceum can inhibit calcium influx and reduce blood pressure. This article discusses the use of natural herbs in treating hypertension. One such herb is Rhaptopetalum coriaceum oliver, which was the first potent drug used for long-term hypertension treatment. Another powerful hypotensive plant is Rauwolfia serpentina, which has been used in Hindu medicine for snakebite and insomnia. Radish extract has also been found to have antihypertensive activity, mediated through activation of muscarinic receptors. Pomegranate juice has been shown to reduce the activity of angiotensin converting enzymes, but clinical research results are contradictory. Finally, the root of the Kudzu plant is officially listed and used in China as a muscle relaxant, antipyretic, and for the treatment of dysentery and hypertension. Pycnogenol, an extract from French maritime pine bark, has been shown in clinical research to modestly lower blood pressure in people with mild hypertension. The aqueous extract of the leaves of Nela nelli, a diuretic and traditional medicine plant, produced a significant fall in mean diastolic, systolic, and mean arterial pressures in a graded dose-response manner in anesthetized NMT male rabbits. Phyllanthus amarus produced antihypertensive effects in anesthetized rats in a dose-dependent manner. The crude extract fraction and all pure compounds from Peganum harmala cause a fall in systolic, diastolic, and mean blood pressure in a dose-dependent manner with a brief effect. The water extract of the stem bark of Ocimum basilicum produces a dose-dependent reduction in mean arterial blood pressure. The ethanol extract of the plant stem bark of Musanga cecropiodes has been reported to have antidiarrheal activity and causes a fall in systolic, diastolic, and mean blood pressure in a dose-dependent manner. The crude extract of the leaves of Moringa oleifera has been shown to have hypotensive effects in anesthetized rats. Tomato extract, which contains carotenoids and antioxidants, has been shown to modestly reduce blood pressure in patients with mild hypertension. Extracts from Lumnitzera racemosa and Linum usitatissimum have also been found to have antihypertensive effects. Flaxseed, which is rich in omega-3 fatty acids, may protect against cardiovascular disease and reduce cholesterol levels. Lepidium latifolium, also known as Stone breaker, has been found to have a hypotensive effect due to its diuretic action in rats. The antihypertensive effects of natural herbs have been studied extensively. The crude extract of Lavandula stoechas has been shown to produce a fall in blood pressure and heart rate, with antihypertensive and bradycardia effects mediated through mechanisms similar to acetylcholine. Clinical trials of a standardized dose of Hibiscus sabdariffa (HS) have shown reliable evidence of antihypertensive effects, with chronic administration reversing cardiac hypertrophy in renovascular hypertensive rats. The antihypertensive effects of HS have been attributed to mediation through acetylcholine and histamine-like dependent mechanisms through direct vasorelaxant effects. Roselle, or calyx of HS, has also been extensively studied for its antihypertensive properties. Gossypium barbadense and Glycine max have shown modest to strong reductions in mean arterial pressure, while Fuchsia magellanica reduces body temperature, acts as a diuretic, and lowers blood pressure. This article discusses the use of natural herbs in the treatment of hypertension. The cardiovascular pharmacology of aqueous extracts of various plants, including Clematis chinensis, Desmodium styracifolium, Daucus carota, Cuscuta reflexa, and Crinum glaucum, were studied in vitro and in vivo. Results showed that some extracts produced a hypotensive activity through vasorelaxation resulting from nitrous oxide stimulation or blockade of calcium channels. Other extracts also showed antioxidant activity and a tonic action on cardiac myocytes. Grataegic acid was identified as the hypotensive principle in Crataegus. In experiments with anesthetized rabbits, intravenous administration of the extract preparation lowered the BP for up to 3 hours. Natural herbs have been used for thousands of years in China to treat hypertension. Hawthorn, specifically, has been found to lower blood pressure due to its flavonoids and oligomeric procyanidins, which act as potent antioxidants. Cat's claw contains rhynchophylline, an alkaloid that inhibits platelet aggregation and thrombosis, potentially preventing strokes and heart attacks. Virginia dayflower extract has been shown to decrease tension in isolated guinea pig aorta rings. Coleonol, found in the plant Coleus forskohlii, has been reported to cause a fall in systolic and diastolic blood pressure. Black bean extract reduces blood pressure by inhibiting calcium influx through receptor-operated and voltage-sensitive channels. Cassia extract has a relaxant effect on aortic rings and may reduce blood pressure by inhibiting calcium influx. Coffee weed leaf extract produces a dose-related decrease in blood pressure and heart rate. Finally, Chaksu extract has been reported to lower blood pressure after intravenous administration. Various natural herbs have been studied for their potential to treat hypertension. The crude extract of Carum copticum produces a dose-dependent decrease in blood pressure and slight bradycardia in rats. Capparis cartilaginea has been shown to decrease the risk of developing hypertension. Green tea and oolong tea show no effect on blood pressure in people with hypertension, while black tea supplement can modestly lower blood pressure. Plantago psyllium and oat cereals have been found to significantly reduce both systolic and diastolic blood pressure. Soluble fiber-rich whole oats can reduce the need for antihypertensive medication and improve blood pressure control. Breadfruit leaf extract, Artocarpus altilis, and Aristolochia manshuriensis have hypotensive properties. Fresh celery juice mixed with vinegar can relieve symptoms associated with hypertension. Apium graveolens has also been reported to reduce systolic and diastolic blood pressure in human beings. This article discusses the use of natural herbs in the treatment of hypertension. Celery has been effective in reducing hypertension in Chinese patients by acting upon the liver. Annona leaf extract has been reported to lower blood pressure by decreasing peripheral vascular resistance. Garlic has antioxidative and antihypertensive effects, with preparations found to be superior to placebo in reducing blood pressure. Buchu is an effective diuretic and anti-inflammatory agent. However, more scientific research needs to be done to verify the effectiveness and safety profile of such herbal remedies. Studies have been conducted on local plants with hypotensive and antihypertensive therapeutic values. Hypertension (HTN) is a major risk factor for coronary artery disease, stroke, and kidney failure. Conventional medicines are commonly used for its treatment. Essential HTN is poorly understood, but it is known to be highly heritable and caused by more than one gene. Secondary HTN is caused by identifiable conditions such as Cushing's syndrome or insulin resistance. Risk factors for developing HTN include hyperthyroidism, hypothyroidism, adrenal gland cancer, kidney disease, obesity/metabolic disorder, pre-eclampsia during pregnancy, coarctation of the aorta, prescription and illegal drugs, high fructose corn syrup consumption, sympathetic nervous system overactivity, elevated renin, family history of HTN, inherited genetic mutations, aging, vitamin D deficiency, alcohol intake, and salt sensitivity. Aggressive BP goals are recommended to reduce adverse outcomes. Each increase of 20 mmHg in systolic BP and 10 mmHg in diastolic BP doubles the risk of a fatal coronary event. Endothelial changes may be associated with essential HTN. Mechanisms associated with secondary HTN are generally understood. Secondary HTN is treated differently than essential HTN by treating the underlying cause of elevated BP. Hypertension, or high blood pressure, affects a large percentage of the population and is caused by factors such as obesity, sedentary lifestyle, stress, and potassium deficiency. Essential hypertension is the most common type, affecting 90-95% of patients. It can be classified as primary or secondary, with primary hypertension having no identifiable medical cause. Hypertension can lead to serious health complications such as strokes, heart attacks, and chronic kidney failure. Treatment can include lifestyle changes, medications, and the use of natural herbs with hypotensive properties. Hypertension (HTN) can lead to serious health conditions such as heart disease, stroke, kidney disease, and blindness. Conventional antihypertensives often have side effects, which is why about 75 to 80% of the world population use herbal medicines for primary health care. Over the past three decades, research has been conducted on local plants with hypotensive and antihypertensive therapeutic values. Some of these medicinal plants have been validated for their effectiveness, but more scientific research is needed to verify their safety profile for their antihypertensive potential. Ayurvedic knowledge needs to be coupled with modern medicine. The article discusses the potential benefits of using natural herbs in the treatment of hypertension. Several herbs, including garlic, hawthorn, and ginger, have been found to have positive effects on blood pressure and cardiovascular health. However, it is important to consult with a healthcare professional before incorporating these herbs into a treatment plan, as they may interact with other medications. The article emphasizes the need for further research on the efficacy and safety of natural herbs as a treatment option for hypertension.