Summary Recovery from stroke: current concepts and future perspectives | Neurological Research and Practice | Full Text neurolrespract.biomedcentral.com
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The article emphasizes the importance of enhancing neurorehabilitation due to the rising number of stroke survivors, while also highlighting effective treatments such as thrombolysis and thrombectomy for minimizing stroke-related complications.
Slides
Slide Presentation (11 slides)
Key Points
- Stroke is a leading cause of permanent disability worldwide.
- Advancements in acute stroke treatment have not fully addressed functional limitations and decreased quality of life for many patients.
- Thrombolysis and thrombectomy are effective treatments, but only a small minority of patients meet the criteria for receiving them.
- The proportional recovery rule may overestimate recovery relationships after stroke, particularly for patients with severe deficits.
- Recovery of hand motor function after stroke is associated with increases in fMRI signals and can be enhanced through training-based interventions and brain stimulation techniques.
- Measures of TMS-evoked EEG responses can predict initial motor deficit and subsequent recovery after stroke.
- Understanding intracortical projections and molecular events involved in axonal sprouting is important for stroke recovery.
- Future perspectives on stroke recovery include biomarkers, motor behavior modulation, neural activity, and cortical activity modeling.
Summaries
34 word summary
Stroke is a major cause of permanent disability globally. The article discusses the need for improved neurorehabilitation as the number of stroke survivors increases. Thrombolysis and thrombectomy are effective treatments for reducing stroke-related complications.
38 word summary
Stroke is a leading cause of permanent disability worldwide, and new strategies are needed to improve neurorehabilitation as the number of stroke survivors continues to rise. Thrombolysis and thrombectomy are effective treatments for reducing stroke-related morbidity and mortality
445 word summary
Stroke is a leading cause of permanent disability worldwide. Despite advancements in acute stroke treatment, many patients still experience functional limitations and a decreased quality of life. As the number of stroke survivors continues to rise, new strategies are needed to improve neurorehabilitation
Thrombolysis and thrombectomy are effective treatments for reducing stroke-related morbidity and mortality, but only a small minority of patients meet the criteria to receive them. In larger regional registries, the percentage of stroke patients receiving thrombolysis is
The proportional recovery rule, which suggests that recovery of function after a stroke is a neurobiological process unaffected by therapy intensity, has been criticized for overestimating recovery relationships. Some patients, particularly those with severe deficits, do not follow this rule.
Recovery of hand motor function after stroke is associated with increases in fMRI signals, which return to levels observed in healthy controls with good functional recovery. The impact of motor impairment and activity changes post-stroke is significant. Connectivity changes in the brain are
Training-based interventions such as physical, occupational, or language therapy, as well as non-invasive brain stimulation techniques like transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (TDCS), have been shown to enhance functional
Measures of TMS-evoked EEG responses in the early days after stroke are closely related to the initial motor deficit and subsequent recovery after 3 months. TMS-EEG can reveal differential response patterns that correlate with recovery, even in patients with
This article discusses various studies and concepts related to stroke recovery. It highlights the importance of understanding the patterns of intracortical projections after a stroke and the molecular, cellular, and functional events involved in axonal sprouting. The concept of diasch
This text excerpt includes references to various articles and studies related to stroke recovery. The mentioned articles cover topics such as endovascular thrombectomy, the potential benefits of music playing in motor rehabilitation, reorganization of cerebral networks after stroke, connectivity-based approaches
This summary provides a concise version of the text excerpt while preserving important details and highlighting key points.
The text excerpt consists of various articles related to stroke recovery and its future perspectives. These articles cover a range of topics, including biomarkers of post-stroke
This text excerpt consists of a list of references to various studies on stroke recovery and related topics. The studies cover a range of subjects, including motor behavior modulation, inter-individual variability in motor recovery, neural activity after stroke, cortical activity modeling, the
This article discusses current concepts and future perspectives on the recovery from stroke. It includes references to various studies and research articles that explore topics such as brain stimulation for treating stroke-related motor deficits, the contribution of ipsilateral brain regions to movement kinematics, cortical